Low Dose Naltrexone (LDN)


Naltrexone is an FDA-approved opiate antagonist that has traditionally been used to wean alcoholics and opioid dependent drug users off the substances, but, in a low dose (referred to as “low dose naltrexone” which is approx. 1/10 the dose used for drug/alcohol rehabilitation), can boost the immune system — helping those with HIV/AIDS, cancer, autoimmune diseases, and central nervous system disorders.

Low dose naltrexone blocks the opiate receptor for about four hours which causes a rebound effect resulting in a dramatic increase in endogenous opiate production.

“Certain medications will work against the naltrexone such as Hydrocodone, Oxycodone, Oxymorphone and other opiate/opioid narcotics. These medications should not be taken while on Naltrexone, as nausea, vomiting, cold sweats, chills, and sometimes numbness in the limbs may occur. Naltrexone may also interfere or counteract both low and high doses of over-the-counter NSAID medications.”

Amazingly, LDN can reduce inflammation and oxidative stress, modulate the immune system, and even inhibit cancer cell proliferation.

LDN is generally used in doses ranging from 3-4.5 mg daily, but many people start at 1.4 mg and work their way up. People with multiple sclerosis (MS) and muscle spasticity tend to do better on a 3 mg dose than the standard 4.5 mg dose recommended for neurodegenerative disorders.

What Conditions Does LDN Treat ?

CancersBladder Cancer
Breast Cancer
Colon & Rectal Cancer
Liver Cancer
Lung Cancer (Non-Small Cell)
Lymphocytic Leukemia (chronic)
Lymphoma (Hodgkin’s and Non-Hodgkin’s)
Malignant Melanoma
Multiple Myeloma
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer (untreated)
Renal Cell Carcinoma
Throat Cancer
Uterine Cancer

ALS (Lou Gehrig’s Disease)
Alzheimer’s Disease
Autism Spectrum Disorders
Hereditary Spastic Paraparesis
Multiple Sclerosis (MS)
Parkinson’s Disease
Primary Lateral Sclerosis (PLS)
Progressive Supranuclear Palsy


Other Autoimmune DiseasesAnkylosing Spondylitis
Behcet’s Disease
Celiac Disease
Chronic Fatigue Syndrome
CREST syndrome
Crohn’s Disease
Hashimoto’s Thyroiditis
Irritable Bowel Syndrome (IBS)
Myasthenia Gravis (MG)
Nephrotic Syndrome
Rheumatoid Arthritis
Sjogren’s Syndrome
Stiff Person Syndrome (SPS)
Systemic Lupus (SLE)
Ulcerative Colitis
Wegener’s Granulomatosis

Other Diseases
Common Colds (URI’s)
Emphysema (COPD)

How to Get LDN if You GP/Doctor Refuses…

If you decide to go the self medicating route, there are places that you can get LDN without a prescription by clicking here.

Mickie Stacey is the founder of Stop the Lyme Lies; a patient advocacy and information website for Lyme & MSIDS (Multisystemic Infectious Diseases Syndrome). She holds a BA (Hons) Arts & Humanities degree and is also a qualified Naturopathic Nutritionist. Mickie freelances for several online publications. When she’s not writing she enjoys printmaking and spending time with her family.

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